False starts in translational control of gene expression
نویسندگان
چکیده
منابع مشابه
False starts Inverse genetics
The concept of reversed — or, as I prefer to call it, reverse — genetics was first formulated by Charles Weissmann in 1978 (Trends Biochem Sci 1978, 3:N109). In this form of genetics, a nucleic acid was modified at a predetermined position in vitro, and the phenotypic effects of this mutation were then assayed either in vitro or in vivo. In contrast, the classical form of genetics relies on fir...
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In the past decade, translational control has been shown to be crucial in the regulation of gene expression. Research in this field has progressed rapidly, revealing new control mechanisms and adding constantly to the list of translationally regulated genes. There is accumulating evidence that translational control plays a primary role in cell-cycle progression and cell differentiation, as well...
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A primary difference between spontaneous speech and read speech concerns the use of false starts, where a speaker interrupts the flow of speech to restart his or her utterance. A study examined the acoustic aspects of such restarts in a widely-used speech database, examining approximately 1000 utterances, about 10% of which contained a restart. Identifying the type of restart in such cases coul...
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I don’t know whether anybody else has noticed the distinct decline in recent years of cases of scientific fraud, plagiarism and other deviations of our noble profession. It seems to me that about a decade ago not a week passed without screaming headlines of faked experiments, cooked results and the lifting of other people’s work. I have been thinking about possible reasons for the decline since...
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ژورنال
عنوان ژورنال: Nature
سال: 1985
ISSN: 0028-0836,1476-4687
DOI: 10.1038/316580a0